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Nanotechnology is currently the most rapidly growing field of science with a vast potential for industrial applications. It builds on the intentional and controlled generation of novel arrangements of atoms at the nanometer scale (1-100 nm). Many manufactured NPs display very special chemical properties due to their size, shape, charge, composition and structure, and are used in a number of products with many more applications on the horizon. Despite the wide array of applications that might lead to unintentional environmental exposure there is a lack of knowledge regarding the ecological and ecotoxicological consequences of an exposure to man-made NPs.
During the last decade a multitude of studies have studied the toxicological effects of a wide range of NPs. These studies have focused on well-characterized particles and their effects in controlled laboratory environments, using both cell based assays and animal and plant tests. These studies have generated a lot of knowledge regarding NP toxicity and how NP toxicity is dependent on the characteristics of the particles, characteristics such as size, charge and shape. However, very little is known about how NP toxicity is altered when the NPs enter the aquatic environment. Weathering, ageing and the formation of bio coronas can affect NP toxicity.
The MISTRA funded Nano safety project will focus on the fate of nanomaterials in semi-natural experimental wetland systems, at simulated realistic surface water conditions and conditions during waste handling, and how the ageing of NPs under these conditions will affect NP toxicity. The MISTRA nanosafe project is a collaborative project between seven Universities in Sweden and Denmark together covering a wide range of expertize. The successful PhD candidate will conduct research within this project with the focus of testing the toxicity of pristine and weathered NPs on fish derived cell lines and also fish embryos. Besides utilizing traditional cell based assays the aim is to optimize novel cell based test systems for NP toxicity assessment. The project requires a good understating of cell based in vitro systems but also in vivo testing using fish and basic ecotoxicological concepts.
The main task is to conduct the PhD thesis work under supervision, which includes development of the PhD student’s methodology, experience, analytical skills, and theoretical depth and breadth. Techniques used within the project include in vitro cell techniques and embryo toxicity tests, quantitative PCR, biochemical assays, and in vivo studies using fish. The studies will primarily be conducted via laboratory studies. Specific research topics associated with the research project include fish physiology, toxicity screening, environmental pollution and toxicology. Shorter periods may also be spent as field work or in another country.
The PhD student will carry out original research in consultation with the supervisors, and complete coursework throughout the period of appointment (totaling 60 hp, or about 1 year’s full time study). Results will be communicated in the form of scientific articles, conference presentations, etc. and a PhD thesis. The PhD student will be supervised by Pro. Joachim Sturve and Dr. Tobias Lammel who will be co- supervisor.
Rules regarding education and employment on a doctoral level are given in Högskoleförordningen (HF, SFS 1993:100). Only
applicants who are admitted to the postgraduate level may be hired. Upon appointment the degree of ability to successfully
complete the PhD program must firstly be evaluated.
The employment is planned to start in September 2019 or upon agreement. The University practice a local agreement
about wage setting for PhD students.
For more information and how to apply
In order to apply for a position at the University of Gothenburg, you have to register an account in our online recruitment
system. It is the responsibility of the applicant to ensure that the application is complete in accordance with the instructions
in the job advertisement, and that it is submitted before the deadline. Use this link:https://www.gu.se/omuniversitetet/aktuellt/lediga-jobb/Lediga_anstallningar-detaljsida/?id=4464
In connection to this recruitment, we have already decided which recruitment channels we should use. We therefore decline further contact with vendors, recruitment and staffing companies.
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