Postdoctoral researcher position to Dept. Biomedical Science, focus: Carbohydrate polymers - proteins interactions

Malmö

Ref REK 2021/185

About Malmö University

Malmö University is an innovative, urban and international institute of higher education, located in the center of Malmö. We have around 1,800 employees and 24,000 students. Malmö University is organized into five faculties: Faculty of Health and Society, Culture and Society, Education and Society, Faculty of Odontology and Technology and Society. The Department of Biomedical Science, Faculty of Health and Society, offers a programme leading to a professional qualification, Biomedical Scientist (first cycle, 180 credits), and a Masters' programme, Biomedical Surface Science (second cycle, 120 credits), as well as first and second cycle freestanding courses. The Department negotiates the multifaceted intersection between biology, chemistry, medicine, physics, and technology and the interdisciplinary approach to research and education aims to further the theoretical and practical understanding of the complex subject matter. Drawing on the balance between pure and applied research, the Department has been successful in attracting funding from regional, national, and international research funding bodies. The research at the faculty is also linked to the research center Biofilms - Research Center for Biointerfaces, which combines biomedical science with clinical and translational research in medical, dental, food and environmental application areas in close collaboration with regional industry.

 

About the position

Protein-based therapeutics are becoming increasingly popular in medicine. Compared to low molecular drugs, they are more specific, cause fewer side effects and are environmentally friendly. They are however more sensitive to the conditions of the surroundings and need to be specially formulated to preserve their structure and function. Another challenge in designing protein formulations is to provide slow release of proteins during extended time. In this project we will investigate interactions of proteins with carbohydrate - based drug delivery vehicles: starch microparticles. In the excess of water, proteins partition between starch microparticles and surrounding liquid. We explore different approaches for controlling the release rate of proteins from starch microparticles.

 

To stabilize proteins in the formulations they can be dried. In the absence of excipients, the proteins can however change their structure, which may influence their stability. In this part of the project, we will perform studies of structure of proteins imbedded in starch microparticles in the solid state. Furthermore, mechanisms of destabilization of proteins in the solid state and the effects of residual moisture will be investigated.  The project will be performed in collaboration between Malmö University and two companies: Magle Chemoswed and Adroit Science.

Apart from carrying out research within these areas the applicant is expected to take responsibility for the maintenance of the instruments involved and to be active by supervising graduate and postgraduate students and fellow scientists in the techniques and participate in teaching at graduate and postgraduate levels. In addition, the applicant will be expected to take part in applications for external funding to support research activities.

 

Qualifications

 

Specific requirements for this position:

Candidates must have demonstrated scientific competence corresponding to a doctoral degree. The ideal candidate holds a PhD degree in physical chemistry, biochemistry, biophysics, polymer chemistry, physical pharmacy or another relevant discipline. Hands-on experience in some of the following methods is highly valued: small- and wide-angle X-ray diffraction/scattering and other scattering techniques, calorimetry and thermal analysis (DSC, ITC, isothermal microcalorimetry, TGA), water sorption techniques, solution or solid-state NMR. The candidate should also have the ability to work in a team and collaborate with people in complementary disciplines.

 

In addition to formal competence, University employees must possess the personal capacities necessary to perform the duties of the position well and to represent the University in the best possible way. The candidate should have the ability to work in a team and collaborate with people in complementary disciplines. Previous experience from working in research projects that involved both industry and academia is highly valued

 

Assessment criteria

  • The quality and focus of the doctoral thesis
  • Research activities within fields relevant to the appointment in question
  • Documented ability to independently conduct research of a sufficient standard
  • Reflective presentation of their own pedagogical outlook and practices
  • Demonstrated ability to communicate and collaborate with actors in other parts of society with a connection to education and research

 

Further information

Questions related to this position can be addressed to professor Vitaly Kocherbitov, E-mail: Vitaly.Kocherbitov@mau.se, phone: +46 70 7457220.

For general questions regarding employment at Malmö university, contact HR-specialist Jill Moberger +46 (0)40 6657840, jill.moberger@mau.se

In our recruitment work, Malmö University has taken a stand regarding recruitment channels and marketing. We therefore decline all offers of advertising and recruitment assistance in connection with this advertisement.

 

Application

You apply for this position via Malmö University's recruitment system by clicking on the "Apply" button. As an applicant, you are responsible for ensuring that your application is completed in accordance with the advertisement, and that it is provided to the University no later than 15 October 2021. The educational qualifications may be documented with guidance from Qualifications portfolio for lecturers/researchers at Malmö University. See also Appointment Rules at Malmö University. Books and any other documents, such as publications, that cannot be sent electronically should be sent in triplicate in an envelope marked with reference number REK 2021/185 and posted to the HR Department, Malmö University, 205 06 Malmö. If the documents weigh more than 2 kg, they should be sent to the delivery address: HR Department, Malmö University, Matrosgatan 1, 211 18 Malmö, marked with reference number REK2021/185

 

The application must include:

  • Curriculum Vitae
  • Copies of Doctoral degree certificate and other relevant certificates
  • A brief account of scientific, educational and other activities relevant to the position, including a description of how the applicant envisions their future research and teaching
  • List of scientific and educational publications
  • Copies of three most relevant publications

 

Miscellaneous

This is a full-time, one-year position, which can be prolonged beyond the first year. Malmö University is a workplace and higher education institution that is characterised by an open and inclusive approach, where gender equality and equal terms add value to our activities. Malmö University applies individual salary setting.

 

Starting date

1 November 2021 or by agreement.

 

Union representatives

SACO-S: Desirée Annvir, desiree.annvir@mau.se

Lärarförbundet: Carl-Erik Blomberg, carl-erik.blomberg@mau.se

ST/OFR: Aje Carlbom aje.carlbom@mau.se

 

 

We are looking forward to receiving your application!

 


Du ansöker senast 2021-10-15 genom att klicka på knappen nedan.