at the Department of Enviromental Science Closing date: 16 May 2021.

The Department of Environmental Science is one of the biggest departments at the Faculty of Science. The department is divided into four units with more than 170 researchers, teachers, doctoral students and technical/administrative staff from over 30 countries. Research and teaching focuses on chemical contaminants, atmospheric science, biogeochemistry and toxicology. As an employee at the Department of Environmental Science you will be part of a dynamic environment with research in leading research areas and with a strong international profile.

Research at the Atmospheric Science unit focuses on everything from toxicity of air pollutants to studies of climate change. The announced Postdoctoral position will focus on the toxicity of airborne nanoparticles from different modes of transport such as road, rail, air and sea traffic.

Project description
One of the largest sources of air pollution in today's cities is emissions from transports. Despite stricter directives within the EU, these emissions threaten human health and may cause acute asthma symptoms, lung cancer, and premature death. The harmful health effects of airborne particles are strongly associated with the size of the particles. Nanoparticles, which are the smallest particles (<100 nm), have often shown more toxic properties than larger particles of the same material.

A model of the human lung, a so-called Air Liquid Interface (ALI) system, will be used to investigate the toxicity of nanoparticles in vitro. In this exposure system, cultured lung cells are exposed to airborne nanoparticles in a manner that closely resembles the human inhalation process.

The ALI system will be used to test the toxicity of e.g. exhaust fumes from different fuels and brake wear particles in the laboratory, as well as air pollutants in real world environments, e.g. in a road tunnel. The lung cells will be exposed to primary and aged particles. The airborne particles that enter the ALI system will in principle have the same properties as they have when they are inhaled by humans. The harmful effects of the particles, such as the ability to induce cell death, inflammatory markers and DNA damage, will be investigated in collaboration with the Karolinska Institute.

The project is part of a larger project at EU level, called nPETS, where the smallest nanoparticles will be mapped and characterized in a number of different cities; Barcelona, ​​Milan, Thessaloniki, and Stockholm. The Postdoctoral Fellow will be positioned at the Department of Environmental Science at Stockholm University, but he/she must be prepared to collaborate with researchers from Karolinska Institute and Royal Institute of Technology in Stockholm, and also with researchers in the other European cities participating in the project. The project may involve travelling.

Main responsibilities 
We are seeking a highly motivated Postdoctoral Fellow with interest and experience in experimental toxicology. The position involves toxicity studies of airborne transportation particles using an ALI exposure system in laboratory and real world environments. More specifically the project will involve cell culturing, set-up/development of ALI exposure systems, exposure studies in different environments, testing of several toxicity endpoints, as well as problem solving within these areas, reporting and scientific publication. Guidance of a PhD student, which will be employed by the project, will also be part of the work.

Qualification requirements
Postdoctoral positions are appointed primarily for purposes of research. Applicants are expected to hold a Swedish doctoral degree or an equivalent degree from another country.

Assessment criteria
The degree should have been completed no more than three years before the deadline for applications. An older degree may be acceptable under special circumstances, which may involve sick leave, parental leave, clinical attachment, elected positions in trade unions, or similar.

The applicant is expected to be an enthusiastic candidate with a strong knowledge within cell biology and toxicology. Experience in cell culture and toxicity assessment can be meritorious. Previous work with nanoparticles and toxicity testing with a focus on genotoxicity and/or inflammation is preferable and experience in use of air-liquid interface exposures can be meritorious. The candidate must be able to work within a team with scientists from different disciplines and fluency in English is a requirement.

In the appointment process, special emphasis is put on the applicant’s knowledge, experience in laboratory and field work and skills in cell culturing and experimental toxicology.

Terms of employment 
The position involves full-time employment for a maximum of two years, with the possibility of extension under special circumstances. Start date 2021-08-16 or as per agreement.

Stockholm University strives to be a workplace free from discrimination and with equal opportunities for all.

Contact
Further information about the position can be obtained from:
Karine Elihn, Associate professor, telephone: +46 736 55 29 00, Karine.Elihn@aces.su.se, Sarah Steimer, Assistant professor, telephone: +46 8 674 71 71, Sarah.Steimer@aces.su.se

Union representatives
Ingrid Lander (Saco-S), telephone: +46 708 16 26 64, saco@saco.su.se, Alejandra Pizarro Carrasco (Fackförbundet ST/Lärarförbundet), telephone: +46 8 16 34 89, alejandra@st.su.se, and seko@seko.su.se (SEKO).

Application
Apply for the position at Stockholm University's recruitment system. It is the responsibility of the applicant to ensure that the application is complete in accordance with the instructions in the job advertisement, and that it is submitted before the deadline.

Please include the following information with your application

  • Your contact details and personal data
  • Your highest degree
  • Your language skills
  • Contact details for 2–3 references

and, in addition, please include the following documents

  • Cover letter
  • CV – degrees and other completed courses, work experience and a list of publications
  • Copy of PhD diploma
  • Letters of recommendation (no more than 3 files)
  • Publications in support of your application (no more than 3 files).

The instructions for applicants are available at: How to apply for a position.

You are welcome to apply!

Stockholm University contributes to the development of sustainable democratic society through knowledge, enlightenment and the pursuit of truth.

Closing date: 16/05/2021