at the Department of Biochemistry and BiophysicsClosing date: 21 February 2018.

The Department of Biochemistry and Biophysics is mainly located in the Arrhenius Laboratories, which are situated at the University Campus at Frescati. The Science for Life Laboratory is also closely linked to the department. Presently more than 250 people are working at the department, of which around 100 are PhD students, engaged in internationally highly recognized research. The research projects span across a broad range of topics covering various aspects of structure and function of biological systems. The combination of the highly interdisciplinary expertise and research projects at the department is unique in Sweden and also at an international level. This expertise ranges across cell biology, biochemistry, biophysics, neurochemistry and theory. For more information about the department, see: www.dbb.su.se.

Project description
Your studies in Bioinformatics will be in the project: Inference of protein function from domain architecture and orthology. Project leader: Professor Erik Sonnhammer.

The function of a protein is very challenging to establish experimentally. A faster route is to predict the function based on the amino acid sequence. This project will employ several approaches that use sequence features to this end. The main goal is to develop computational tools for studying domain architecture evolution and its relation to function and orthology.

The project includes both development of new algorithms and methods, as well as applications such as tools and workbenches to enable public access for database queries of Pfam, InParanoid, and Hieranoid. The methods include hidden Markov models, clustering methods, various statistical analyses, and own developed algorithms. The project involves programming, data analysis, benchmarking, as well as application of the developed methods to genes of particular interest in order to discover new protein functions.

The successful candidate should have an M.Sc. in bioinformatics or related field, and knowledge of molecular biology. Alternatively, an M.Sc. in molecular biology or related field and at least 1 year of practical experience in bioinformatics research. Familiarity with sequence analysis techniques is essential, as well as a high level of motivation. Computer programming (e.g. Perl, Python, R, C++, Java), UNIX skills, and knowledge of biological database systems are necessary merits.

Qualification requirements
In order to meet the general entry requirements, the applicant must have completed a second-cycle degree, completed courses equivalent to at least 240 higher education credits, of which 60 credits must be in the second cycle, or have otherwise acquired equivalent knowledge in Sweden or elsewhere.

In order to meet the specific entry requirements, for acceptance in the Biochemistry, especially Bioinformatics, program the applicant must have passed courses within the first and second cycles of at least 90 credits in either, a) Chemistry/Molecular Biology/Biotechnology, or b) Computer Science/Mathematics/Physics and at the second cycle level, 60 credits in Life Science, Computer Science Mathematics, Physics or Bioinformatics including a 30 credit Degree Project (thesis).

The qualification requirements must be met by the deadline for applications.

Selection
The selection among the eligible candidates will be based on their capacity to successfully complete the program. Important criteria when assessing this capacity are; documented knowledge and skills in the field of the thesis project, written and oral proficiency in English, the capacity for analytical thinking, the ability to collaborate, as well as creativity, initiative and independence. The assessment will be based on previous experience and grades, the quality of the degree project, references, relevant experience, interviews and the candidate’s written motivation for seeking the position.

Admission Regulations for Doctoral Studies at Stockholm University are available at: www.su.se/rules.

Terms of employment
Only a person who will be or has already been admitted to a third-cycle programme may be appointed to a doctoral studentship.

The term of the initial contract may not exceed one year. The employment may be extended for a maximum of two years at a time. However, the total period of employment may not exceed the equivalent of four years of full-time study.

Doctoral students should primarily devote themselves to their own education, but may engage in teaching, research, and administration corresponding to a maximum of 20 % of a full-time position.

Please note that admission decisions cannot be appealed.

Stockholm University strives to be a workplace free from discrimination and with equal opportunities for all.

Contact
For more information, please contact the project leader, Professor Erik Sonnhammer, erik.sonnhammer@scilifelab.se.

General information about the PhD programs can be given by Pia Ädelroth, pia.adelroth@dbb.su.se or Head of the Department, Lena Mäler, lenam@dbb.su.se.

Union representatives
Ingrid Lander (Saco-S) and Lisbeth Häggberg (Fackförbundet ST and Lärarförbundet), telephone: +46 8 16 20 00 (operator), seko@seko.su.se (SEKO), and PhD student representative, doktorandombud@sus.su.se.

Application
Apply for the PhD student position at Stockholm University's recruitment system by clicking the "Apply" button. It is the responsibility of the applicant to ensure that the application is complete in accordance with the instructions in the job advertisement, and that it is submitted before the deadline.

Please include the following information with your application

  • Your contact details and personal data
  • Your highest degree
  • Your language skills
  • Contact details for 2–3 references

and, in addition, please include the following documents

  • Cover letter
  • CV – degrees and other completed courses, work experience and a list of degree projects/theses
  • Research proposal (no more than 3 pages) describing: 
    – why you are interested in the field/project described in the advertisement 
    – why and how you wish to complete the project 
    – what makes you suitable for the project in question
  • Degree certificates and grades confirming that you meet the general and specific entry requirements (no more than 6 files)
  • Letters of recommendation (no more than 3 files)
  • Degree projects/theses (no more than 3 files)
  • A computer code you have written (1 file).

The instructions for applicants are available at: Instructions – Applicants.

You are welcome to apply!

Vi är ett av Europas ledande universitet i en av världens mest dynamiska huvudstäder. En relation med Stockholms universitet är meriterande oavsett om du är student, forskare eller intressent. Hos oss ger utbildning och forskning resultat.

Closing date: 21/02/2018