at the Department of Biochemistry and BiophysicsClosing date: 21 February 2018.

The Department of Biochemistry and Biophysics is mainly located in the Arrhenius Laboratories, which are situated at the University Campus at Frescati. Presently more than 250 people are working at the department, of which around 100 are PhD students, engaged in internationally highly recognized research. The research projects span across a broad range of topics covering various aspects of structure and function of biological systems. The Science for Life Laboratory is also closely linked to the department. The combination of the highly interdisciplinary expertise and research projects at the department is unique in Sweden and also at an international level. This expertise ranges across cell biology, biochemistry, biophysics, neurochemistry and theory. For more information about the department, see: www.dbb.su.se.

Project description
Your studies in Biochemistry will be in the project: Mitochondrial protein synthesis och aging. Project leader: Professor Martin Ott.

Mitochondria convert chemical energy into ATP by utilizing a system of molecular machines, the respiratory chain complexes. The complexes driving oxidative phosphorylation are a mosaic of proteins encoded by the nuclear and the mitochondrial DNA. Therefore, assembly of the respiratory chain and the ATPase requires not only expression and import of many nuclear encoded proteins but also translation of mitochondrially encoded proteins. The mitochondrial genetic system is responsible for replication and transcription of the mitochondrial genome and for the synthesis of a few polypeptides within the organelle. Dysfunction of these processes underlies many human disorders and aging. It is therefore surprising that so little is known about mitochondrial protein synthesis. We aim at elucidating how accuracy of mitochondrial translation is achieved and how changed accuracy impacts the aging process. We will employ a wide array of methodology including yeast genetics, biochemistry, structural biology (high-resolution cryo-EM) and biophysics. Candidates should have a master's degree in biochemistry, molecular biology or similar discipline

Qualification requirements
In order to meet the general entry requirements, the applicant must have completed a second-cycle degree, completed courses equivalent to at least 240 higher education credits, of which 60 credits must be in the second cycle, or have otherwise acquired equivalent knowledge in Sweden or elsewhere.

In order to meet the specific entry requirements, for acceptance in the Biochemistry program the applicant must have passed courses within the first and second cycles of at least 120 credits in Biochemistry/Life Science, including at least 15 credits Biochemistry at the second cycle level and a Degree Project (thesis) also in Biochemistry of 30 credits.

The qualification requirements must be met by the deadline for applications.

Selection
The selection among the eligible candidates will be based on their capacity to successfully complete the program. Important criteria when assessing this capacity are; documented knowledge and skill in the field of the thesis project, written and oral proficiency in English, the capacity for analytical thinking, the ability to collaborate, as well as creativity, initiative, and independence. The assessment will be based on previous experience and grades, the quality of the degree project, references, relevant experience, interviews and the candidate’s written motivation for seeking the position.

Admission Regulations for Doctoral Studies at Stockholm University are available at: www.su.se/rules.

Terms of employment
Only a person who will be or has already been admitted to a third-cycle programme may be appointed to a doctoral studentship.

The term of the initial contract may not exceed one year. The employment may be extended for a maximum of two years at a time. However, the total period of employment may not exceed the equivalent of four years of full-time study.

Doctoral students should primarily devote themselves to their own education, but may engage in teaching, research, and administration corresponding to a maximum of 20 % of a full-time position.

Please note that admission decisions cannot be appealed. 

Stockholm University strives to be a workplace free from discrimination and with equal opportunities for all.

Contact
For more information, please contact the project leader, Professor Martin Ott, martin.ott@dbb.su.se.

General information about the PhD programs can be given by Pia Ädelroth, pia.adelroth@dbb.su.se or Head of the Department, Lena Mäler, lenam@dbb.su.se.

Union representatives
Ingrid Lander (Saco-S) and Lisbeth Häggberg (Fackförbundet ST and Lärarförbundet), telephone: +46 8 16 20 00 (operator), seko@seko.su.se (SEKO), and PhD student representative, doktorandombud@sus.su.se.

Application
Apply for the PhD student position at Stockholm University's recruitment system by clicking the "Apply" button. It is the responsibility of the applicant to ensure that the application is complete in accordance with the instructions in the job advertisement, and that it is submitted before the deadline. Please include the following information with your application

  • Your contact details and personal data
  • Your highest degree
  • Your language skills
  • Contact details for 2–3 references

and, in addition, please include the following documents

  • Cover letter
  • CV – degrees and other completed courses, work experience and a list of degree projects/theses
  • Research proposal (no more than 3 pages) describing: 
    – why you are interested in the field/project described in the advertisement 
    – why and how you wish to complete the project 
    – what makes you suitable for the project in question
  • Degree certificates and grades confirming that you meet the general and specific entry requirements (no more than 6 files)
  • Letters of recommendation (no more than 6 files)
  • Degree projects/theses (no more than 6 files).

The instructions for applicants are available at: Instructions – Applicants.

You are welcome to apply!

Vi är ett av Europas ledande universitet i en av världens mest dynamiska huvudstäder. En relation med Stockholms universitet är meriterande oavsett om du är student, forskare eller intressent. Hos oss ger utbildning och forskning resultat.

Closing date: 21/02/2018