Researcher in Engineering and Data analysis of nanopore-based biosensors

Reference number PAR 2024/559

The University of Gothenburg tackles society’s challenges with diverse knowledge. 56 000 students and 6 600 employees make the university a large and inspiring place to work and study. Strong research and attractive study programmes attract researchers and students from around the world. With new knowledge and new perspectives, the University contributes to a better future.

The Department of Chemistry and Molecular Biology conducts high-quality research and education in chemical sciences and molecular life sciences. Our research and education focuses on a deep understanding of chemical and biological processes in cells and in the environment. We address important societal issues such as antibiotic resistance, cancer, brain diseases, environmental problems and climate change. In this way, we contribute to achieving the UN's global goals for sustainable development in the areas of good health and well-being, sustainable energy for all, sustainable cities and communities, and combating climate change. The department is an international environment with interdisciplinary collaborations in both research and education, and contributes strongly to the University of Gothenburg's top ranking in life science. The department is responsible for postgraduate education in the subject area Natural Sciences with a focus on chemistry, biophysics, biology and educational science. In addition, the department hosts educational programs in molecular biology, genomics and systems biology, chemistry, organic chemistry and pharmaceutical chemistry, as well as prescription education. The department collaborates with various societal actors such as schools, business and authorities. The Department of Chemistry and Molecular Biology has around 250 employees. We are located in a newly built Natrium building located in the central part of Gothenburg.

Tietze lab is a part of the Wallenberg Centre for Molecular and Translational Medicine (https://www.gu.se/en/molecular-translational-medicine) which conducts basic and clinical research in the fields of metabolism, neuroscience, cancer, inflammation, degenerative diseases, genomics and life science chemistry and composed of 32 research teams on Göteborg’s side which research is focused on important questions in medicine with a special interest in translation molecular medicine. Tietze lab (www.tietze-lab.com) focuses on bioinspired chemical engineering of peptide-based molecules/ materials towards diagnostics and drug delivery. Her research team develops novel approaches to provide access to highly hydrophobic peptides/peptide mimetics, i.e. transmembrane peptides/proteins and venom-derived cysteine-rich peptides. Her lab develops novel conjugation methods, explore SAR properties of novel bioactive peptides, and engineer peptide-based nanosensors.

Duties 

Project

We are seeking a motivated and talented scientist to join our interdisciplinary biosensor development team. Here, you will commit to the development of novel biosensors by using tailormade, microfluidic nanopore-based sensing systems.

What you’ll do

You will work hand in hand with our synthesis and material specialists, working on system integration and data analysis of novel biosensors. Apart from the analysis of large datasets, you will work on the development, optimization and implementation of instrument communication and automatization within our biosensor measurement platform. Additionally, you will be engaged in designing novel sensor units and developing surface modification/functionalization techniques. The candidate will be part of the Wallenberg Centre for Molecular and Translational Medicine in Gothenburg (https://www.gu.se/en/molecular-translational-medicine) and will benefit from the well-established network within the Region Västra Götaland and Sweden. This position is funded by a prestigious Proof of Concept WALP KAW grant.

Job assignments

The candidate will work on the system integration of multiple sensors within a microfluid set-up. Will develop and establish routine experimental workflows using the microfluidic set-up to enable high throughput sample measurements. Additionally, the candidate will optimize data analysis and downstream workflows

Qualifications 

Required education, knowledge and experience, personal qualities

We are looking for a candidate with

  • a PhD degree in system integration, data science, material science or related fields, and has a strong track record in those fields
  • extensive practical knowledge of system engineering, integration and data analysis
  • extensive practical knowledge in nanopore analysis/ analyte detection as well as material characterization techniques of such systems
  • proven experience in machine learning or similar
  • understanding of data structures, data modeling and software architecture
  • deep knowledge of math, probability, statistics and algorithms
  • ability to write robust code in Python
  • familiarity with machine learning frameworks (like Keras or PyTorch) and libraries : scikit-learn
  • great initiative and willingness to implement new ideas and approaches, but also strong problem-solving capabilities.
  • experience in presenting scientific findings in writing, presentations, and networking activities with the ability to communicate and write proficiently in English. Furthermore, the applicant must be responsible, and committed, be able to work independently, and collaborate with scientists from other disciplines in lab and team environments.

Merit education, knowledge and experience, personal qualities

The successful applicant is expected to plan, execute and analyse experiments in an independent manner and to actively contribute scientifically to the group.

Employment 

Fixed term, fulltime 100% during 360 days. 

Contact information for the post 

If you have any questions about the position, please contact Alesia A. Tietze, Universitetslektor (Associate Professor) Alesia.a.tietze@gu.se

Unions 

Union representatives at the University of Gothenburg can be found here: https://www.gu.se/om-universitetet/jobba-hos-oss/hjalp-for-sokande 

Application 

To apply for a position at the University of Gothenburg, you have to create an account in our recruitment system. Submit your application via the University of Gothenburg’s recruitment portal by clicking the “Apply” button. It is your responsibility to ensure that the application is complete as per the vacancy notice, and that the University receives it by the final application deadline. . The application shall include:

  • Cover letter with an explanation of why you apply for the position
  • CV including scientific publications
  • Copies of exam certificates
  • At least two references (name, telephone no, relation)

Applications must be received by: 2024-07-31

The University works actively to achieve a working environment with equal conditions, and values the qualities that diversity brings to its operations.

Salaries are set individually at the University.

In accordance with the National Archives of Sweden’s regulations, the University must archive application documents for two years after the appointment is filled. If you request that your documents are returned, they will be returned to you once the two years have passed. Otherwise, they will be destroyed.

In connection to this recruitment, we have already decided which recruitment channels we should use. We therefore decline further contact with vendors, recruitment and staffing companies.