Research Assistant

The University of Gothenburg tackles society’s challenges with diverse knowledge. 56 000 students and 6 600 employees make the university a large and inspiring place to work and study. Strong research and attractive study programmes attract researchers and students from around the world. With new knowledge and new perspectives, the University contributes to a better future.

The Institute of Biomedicine is involved in both research and education. In both of these areas, we focus on fundamental knowledge of the living cell – what it consists of, how it works, how its function is directed by the genetic material, and how it interacts with various kinds of micro-organisms. Using this knowledge, we try to elucidate the causes of diseases, and find new ways to diagnose and treat them.

The Institute is composed of the following four departments:

• The Department of Infectious Diseases
• The Department of Microbiology and Immunology
• The Department of Medical Biochemistry and Cell Biology
• The Department of Laboratory Medicine

At present, the institute has about 340 employees and approximately 450 million SEK in total assets.

Human pluripotent stem cells (hPSCs) have near-indefinite expansion potential, and the ability to differentiate into every cell type in the body. As in vitro differentiation of hPSCs mimics defined processes of embryonic development, it represents a promising model to dissect the molecular impact of pre-leukemic mutations that may arise before birth, and that underly the emergence of childhood leukemia. However, the development of the blood system is especially challenging to model in vitro, as embryonic blood develops through successive waves in multiple anatomical locations, in close association with the endothelial cells forming the developing circulatory system. Our research group harnesses novel hPSC differentiation protocols as well as emerging single-cell profiling technologies to address this challenge.

This project aims to identify new regulators of human developmental hematopoiesis and leukemogenesis.

Duties 

The selected candidate will work with human pluripotent stem cell (hPSC) expansion and differentiation, and on the optimization of protocols for lentiviral vector cloning, hPSC transduction and gene expression modulation.

Qualifications 

We are looking for a highly motivated and dedicated candidate, who wishes to gain in-depth expertise in stem cell and developmental biology, hematology and molecular mechanisms of differentiation. This project is intended for a candidate who has completed their Masters degree in the field of molecular and cell biology.

Preference will be given to candidates who already have prior experience in stem cell biology, RT-qPCR, cloning, aseptic cell culture techniques and flow cytometry. Well-ranked candidates showing high interest in acquiring this hands-on training will also be considered.

Employment 

The employment is limited (temporary) for 5 months and full time 100% with placement at the Institute of biomedicine. First day of employment as agreed.

Contact information for the post 

If you have any questions about the position, please contact Carolina Guibentif, phone: +46-702253076, mail: carolina.guibentif@gu.se

Unions 

Union representatives at the University of Gothenburg can be found here: https://www.gu.se/om-universitetet/jobba-hos-oss/hjalp-for-sokande 

Application 

To apply for a position at the University of Gothenburg, you have to create an account in our recruitment system. Submit your application via the University of Gothenburg’s recruitment portal by clicking the “Apply” button. It is your responsibility to ensure that the application is complete as per the vacancy notice, and that the University receives it by the final application deadline. 

Applications must be received by: 2023-12-08

The University works actively to achieve a working environment with equal conditions, and values the qualities that diversity brings to its operations.

Salaries are set individually at the University.

In accordance with the National Archives of Sweden’s regulations, the University must archive application documents for two years after the appointment is filled. If you request that your documents are returned, they will be returned to you once the two years have passed. Otherwise, they will be destroyed.

In connection to this recruitment, we have already decided which recruitment channels we should use. We therefore decline further contact with vendors, recruitment and staffing companies.