Postdoctoral fellow in Viral Immunology
Ref PAR 2023/58
The University of Gothenburg tackles society’s challenges with diverse knowledge. 56 000 students and 6 600 employees make the university a large and inspiring place to work and study. Strong research and attractive study programmes attract scientists and students from around the world. With new knowledge and new perspectives, the University contributes to a better future.
Postdoctoral fellow in Viral Immunology
The Institute of Biomedicine is involved in both research and education. In both of these areas, we focus on fundamental knowledge of the living cell – what it consists of, how it works, how its function is directed by the genetic material, and how it interacts with various kinds of micro-organisms. Using this knowledge, we try to elucidate the causes of diseases, and find new ways to diagnose and treat them.
The Institute is composed of the following four departments:
- The Department of Infectious Diseases
- The Department of Microbiology and Immunology
- The Department of Medical Biochemistry and Cell Biology
- The Department of Laboratory Medicine
At present, the institute has about 360 employees and approximately 450 million SEK in total assets
We are recruiting a postdoctoral fellow to join our dynamic team of immunologists in the laboratory of Davide Angeletti (www.angelettilab.com). The lab is funded by several grants including financing from European Research Council (ERC-StG), Wallenberg Foundations and Ventenskapsrådet. The fellow will work on an exciting project combining state of the art immunological techniques and multicolor flow cytometry with advanced in vivo models to dissect molecular and cellular rules behind B cell immunodominance after influenza infection or vaccination
Subject area description
Influenza virus infection continues to cause significant morbidity and mortality and seasonal vaccines show modest efficacy. The main target of current vaccines is influenza hemagglutinin (HA). We are interested in understanding why our humoral immune system does not recognize all epitopes of HA in the same way. To dissect this we are combining BCR-transgenic mouse models with advanced immunological techniques. By deciphering why some conserved epitopes are not able to elicit a humoral immune response, we hope to be able to design improved, next-generation vaccines.
The successful candidate is expected to work independently and drive the project. They will be responsible for the planning and execution of experiments, analysis and interpretation of the data and writing of manuscripts. Practical work will include handling and genotyping mice, in vivo infection and vaccination, multi-color flow cytometry and other standard immunological techniques.
The eligibility criteria for employing teaching staff are set out in Chapter 4 of the Higher Education Ordinance and in the Appointment Procedure for Teaching Posts at the University of Gothenburg.
To be eligible for appointment as a postdoc, the applicant is required to have a doctoral degree, a doctoral degree in art or a foreign degree that is deemed to be equivalent to a doctoral degree. This eligibility requirement must be met before the employment decision is made.
In the first instance, those who have completed their degree no more than three years prior to the end of the application period shall be considered. Those who have completed their degree more than three years prior to the end of the application period may also be considered in the first instance if special grounds exist. Special grounds relate to leave of absence due to illness, parental leave, commissions of trust within union organisations, service within the defence services or other similar circumstances, as well as clinical service or service/assignment relevant to the subject area.
The successful candidate is required to have a PhD in the Biomedical area, preferably immunology.
The following qualifications are required for the position: 1) extensive experience working with in vivo mouse models including adoptive transfers of immune cells, immunizations and influenza infection 2) experience with analysis of immune cells by multicolor flow cytometry 3) ability to complete projects as demonstrated by at least one first author publications in international peer-reviewed journal.
The following qualifications are strong merits: 1) experience with tetramer staining of B cells, 2) experience in handling influenza virus and performing standard neutralization assays, 3) experience with cytokine profiling.
The candidate is also expected to have excellent proficiency in written and spoken English. Ability to work in a group and personal suitability are of great importance when evaluating applicants.
Regulations for the evaluation of qualifications for academic positions are given in Chapter 4,
Section 3 - 4 of the Higher Education Ordinance.
The employment is full time and temporary, two years with the possibility of one year's extension, with placement at the Institute of Biomedicine. First day of employment as agreed.
If you have any questions about the position, please contact: Davide Angeletti, Research Fellow, 031-7866324 or firstname.lastname@example.org.
Union representatives at the University of Gothenburg can be found here: https://www.gu.se/om-universitetet/jobba-hos-oss/hjalp-for-sokande
Submit your application via the University of Gothenburg’s recruitment portal by clicking the “Apply” button. It is your responsibility to ensure that the application is complete as per the vacancy notice, and that the University receives it by the final application deadline.
The application should contain:
- A cover letter giving a brief description of previous research experience, and a motivation to why you are applying
- A CV including a list of publications
- Contact details of two references
- Proof of completed PhD
Applications must be received by: 230208
Information for International Applicants
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The University works actively to achieve a working environment with equal conditions, and values the qualities that diversity brings to its operations.
Salaries are set individually at the University.
In accordance with the National Archives of Sweden’s regulations, the University must archive application documents for two years after the appointment is filled. If you request that your documents are returned, they will be returned to you once the two years have passed. Otherwise, they will be destroyed.
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