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The Centre for Cellular Imaging (CCI) in operation since 2003, is a national research infrastructure and one of the leading academic imaging facilities in Sweden providing expertise and access to advanced microscopy to the research community, both locally and at other Swedish universities and abroad (https://www.gu.se/en/core-facilities/centre-for-cellular-imaging). The CCI is located at the University of Gothenburg Core Facilities, and is also part of the National Microscopy Infrastructure (https://nmisweden.se/), the Science for Life Laboratory (SciLifeLab, scilifelab.se) and the Euro-BioImaging-ERIC (https://www.eurobioimaging.eu/). The CCI offers high-end imaging techniques for researchers in the various fields of life science, but also chemistry, physics, material science. The equipment includes several laser scanning (confocal and multiphoton) and conventional light microscopes, super-resolution microscopes, MALDI imaging mass spectrometry as well as scanning and transmission electron microscopes. We have also a comprehensive suite of electron microscopy sample preparation labs and equipment for room temperature, microwave and cryoEM preparation, including advanced ultramicrotomy capability. The scientific staff at the CCI assists researchers in the experimental designing and planning of microscopy experiments and provides the in-depth training for the operation of the microscopes and for specific imaging techniques. Additionally, support is provided in the processing, rendering and analysis of the acquired datasets and computational infrastructure for handling big image data. The CCI team has broad interactions with the wider microscopy community and has wide-ranging collaborations with both academic and industrial partners.

The CCI is now recruiting a motivated and experienced Researcher with expertise in Electron Microscopy (EM) and its various applications in life sciences and more specifically in correlative array tomography. The position will involve direct participation in the research projects by performing ultrastructural analysis on various biological specimens including cultured yeast, bacteria, insect, and mammalian cells as well as model organisms such as flies, nematodes, fish, and rodents. The main tasks for the post holder will include sample preparation (chemical and cryo-fixation methods, resin embedding, serial sectioning) imaging (transmission and scanning EM, serial TEM, SEM and TEM tomography), advanced molecular mapping techniques (immuno-EM) and correlative array tomography, training, maintenance, and operations in electron microscopy.

 

Duties

The role of the experienced researcher will work within the Centre for Cellular Imaging national research infrastructure and in direct collaboration with the Cellular and Molecular Imaging SciLifeLab platform. The post-holder will assist in providing outstanding imaging science for researchers, from initial consultation, experiment design through to sample preparation, image acquisition, analysis, and data interpretation. The post-holder will work on multiple imaging projects from research scientists, educating and training of core facility users in to select and apply the appropriate electron microscopy techniques, across a broad range of biomedical research disciplines (cell biology, immunology, infection and immunity, parasitology, cancer biology, neurobiology, biomaterials, clinical research and more). The post-holder will use a range of sample preparation, imaging, and analysis workflows, encompassing electron and light microscopy, often combined into correlative and multimodal pipelines, including full cell/tissue processing (chemically and by cryo), sectioning (plastic embedded) and cryo-sectioning. The post-holder will be also involved in technique and method development projects where the scientific research questions demand new innovations in imaging science, to meet with the users’ needs and participate in the teaching of users and PhD students. The post-holder will also contribute to smooth day-to-day operation of the facility.

Key responsibilities

These include but are not limited to:

  • Contribute to the service provision of an outstanding CCI for our users by producing high quality and timely results on individual projects, from initial consultation through to sample preparation, image acquisition and analysis and data interpretation, as part of the CCI team.
  • Participate in the development of new 3D volume EM techniques under the guidance of the CCI Lead and together with the Cellular and Molecular Imaging Scilifelab platform.
  • Train core facility scientists in all aspects of Electron Microscopy.
  • Assist with general laboratory support including maintenance of microscopes, sample preparation equipment and rooms, purchasing and preparation of consumables including chemicals, buffers, and EM grids.
  • Continuing professional development in the field of Electron Microscopy by attending courses and workshops, presenting work at scientific meetings, and keeping abreast of the relevant literature.

 

Qualifications 

We are seeking for an ambitious and service-oriented team player with excellent interpersonal, project planning, timekeeping, and organizational skills. The candidate should be able to work both independently and as part of the CCI team and enjoy working in an international and highly collaborative and multidisciplinary scientific environment. To take this role the suitable candidate should hold a PhD degree in Science (Biology, Chemistry or Physic), or equivalent degree with a strong research experience in electron microscopy for life science. Expertise in standard resin-embedding preparations of cells and tissues for TEM and SEM, ultramicrotomy, serial sectioning, transmission electron microscopy and advanced volume scanning electron microscopy acquisition is essential; Experience in correlated multimodal imaging workflows, in advanced sample preparation techniques (such as cryo-preparation for example high-pressure freezing, freeze substitution, plunge freezing), immune-EM techniques (e.g. Tokuyasu) and image analysis are desirable. The candidate should be willing to expand his/her knowledge in new imaging techniques and be ready to work in a highly interdisciplinary environment. Ability to manage workload and structure the work with short timelines. We are looking for an enthusiastic person who combines technical expertise with strong communication skills in English, who has a strong will to aid other researcher in their work, but also the motivation to work independently. This post offers an unparalleled opportunity to apply your microscopy skills to exciting and innovative research across biomedical disciplines, with access to cutting edge instrumentation, and the chance to develop completely new imaging techniques and technologies for direct application to biomedical research. The role reports to the Head of the CCI.

 

Employment 

The position is a full-time, permanent position (100%), placed at the Centre for Cellular Imaging (CCI), Sahlgrenska Academy. A probationary employment period of 6 months may be applied. Starting date as agreed.

 

Contact information for the post 

For more information, please contact Julia Fernandez-Rodriguez (phone: +46-(0)31-786 9719, e-mail: juliafer@cci.sahlgrenska.gu.se).

 

Unions 

Union representatives at the University of Gothenburg can be found here: https://www.gu.se/om-universitetet/jobba-hos-oss/hjalp-for-sokande 

 

Application 

To apply for a position at the University of Gothenburg, you have to create an account in our recruitment system. Submit your application via the University of Gothenburg’s recruitment portal by clicking the “Apply” button. It is your responsibility to ensure that the application is complete as per the vacancy notice, and that the University receives it by the final application deadline.

The application shall contain a cover letter, your CV, list of publications, three letters of recommendation, and a summary of experience in the fields of electron microscopy. The application can be submitted in English.

 

Applications must be received by: 2022-06-03

The University works actively to achieve a working environment with equal conditions, and values the qualities that diversity brings to its operations.

Salaries are set individually at the University.

In accordance with the National Archives of Sweden’s regulations, the University must archive application documents for two years after the appointment is filled. If you request that your documents are returned, they will be returned to you once the two years have passed. Otherwise, they will be destroyed.

In connection to this recruitment, we have already decided which recruitment channels we should use. We therefore decline further contact with vendors, recruitment and staffing companies.