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The Department of Chemistry and Molecular Biology conducts high-quality research and education in chemical sciences and molecular life sciences. Our research and education focuses on a deep understanding of chemical and biological processes in cells and in the environment. The department is an international environment with interdisciplinary collaborations in both research and education, and contributes strongly to the University of Gothenburg's top ranking in life science.The department is responsible for postgraduate education in the subject area Natural Sciences with a focus on chemistry, biophysics, biology and educational science.

X-ray diffraction studies of the structure and function of membrane proteins is a strong research activity at the University of Gothenburg. Richard Neutze’s and Gisela Brändén’s research groups have developed methods for time-resolved serial crystallography and time-resolved x-ray solution scattering investigations of conformational changes in membrane proteins. X-ray scattering is not as information rich as x-ray diffraction and therefore structural modelling is challenging. We have collected time-resolved x-ray scattering data at the European Synchrotron Radiation Facility from several different light-sensitive membrane proteins. Molecular dynamics simulations and x-ray scattering calculations are required to fit these difference x-ray scattering data, and these structural models must incorporate both the protein and its surrounding detergent micelle. We are therefore looking for a researcher enginer who can work on the fitting of difference X-ray scattering data recorded at the ESRF so that these data can be brought forward to publication.

Job assignments

We have collected time-resolved x-ray scattering data at the European Synchrotron Radiation Facility from several different light-sensitive membrane proteins. Molecular dynamics simulations and x-ray scattering calculations are required to fit these difference x-ray scattering data, and these structural models must incorporate both the protein and its surrounding detergent micelle. We are therefore looking for a specialist who can work on the fitting of difference X-ray scattering data recorded at the ESRF so that these data can be brought forward to publication. The successful candidate must be familiar with performing molecular dynamics simulations of retinal proteins using Gromacs; must be able to build and energy minimize a detergent micelle within Gromacs; must be familiar with x-ray scattering calculations using Crysol; and must be able to assemble the results from molecular dynamics trajectories and x-ray scattering calculations into structural fitting calculations performed using MatLab. Experience in presenting the results of such an analysis (eg. through manuscripts ) is a merit.

Qualifications

The successful candidate must have a master level qualification in chemistry, molecular biology, structural biology or its equivalent. The successful candidate must also have several years working experience in research using both molecular dynamics simulations (and in particular the programme Gromacs) and X-ray scattering calculations (specifically, using the programme Crysol). The successful candidate must be able to work with retinal proteins in Gromacs, and to be able to create and energy minimize a realistic detergent micelle using Gromacs. The successful candidate must also be familiar with the programming language MatLab. Experience in presenting results from X-ray scattering studies (eg. in publications or a PhD thesis) is a merit.

Employment

Fixed term, full time 100% during 6 months at the Department of Chemistry and Molecular Biology.

For further information regarding the position

Richard Neutze, e-mail: richard.neutze@gu.se

Unions

Union representatives at the University of Gothenburg:
https://www.gu.se/en/about-the-university/work-at-the-university-of-gothenburg/how-to-apply

Information for International Applicants

Choosing a career in a foreign country is a big step. Thus, to give you a general idea of what we and Gothenburg have to offer in terms of benefits and life in general for you and your family/spouse/partner please visit:

https://www.gu.se/en/about-the-university/welcome-services
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How to apply

In order to apply for a position at the University of Gothenburg, you have to register an account in our online recruitment system. It is the responsibility of the applicant to ensure that the application is complete in accordance with the instructions in the job advertisement, and that it is submitted before the deadline. The selection of candidates is made on the basis of the qualifications registered in the application.

You must include the following, in PDF format

  • Personal letter
  • CV
  • Diploma and transcripts showing that you meet with the general entry requirement
  • Proof of completion of  English 6 course or the acquired equivalent knowledge through previous studies
  • Two references (name, e-mail, telephone number, relation)

If your degree is from a university outside of Sweden, check what you need to submit at https://www.universityadmissions.se/en/All-you-need-to-know1/Applying-for-studies/Documenting-your-eligibility-for-studies/Instructions-for-Masters-applicants/Specific-requirements-for-my-country1/ where you can also see what you need to submit in order to fulfill the English language requirement.

If your degree has not been verified by a Swedish authority you need to provide contact details to the issuing university, registrar or similar, that can verify the degree at our request

Closing date: 2021-09-30

The University of Gothenburg promotes equal opportunities, equality and diversity.

Salary is determined on an individual basis.

Applications will be destroyed or returned (upon request) two years after the decision of employment has become final. Applications from the employed and from those who appeal the decision will not be returned.

 

In connection to this recruitment, we have already decided which recruitment channels we should use. We therefore decline further contact with vendors, recruitment and staffing companies.