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Research and graduate education at the department of chemistry and molecular biology comprises a wide scientific field from the atomic and molecular levels all the way through cells to intact organisms. Much of the phenomena studied here impact on our natural environment and living systems. We participate in undergraduate programs in chemistry, molecular biology, medicinal chemistry, biology, marine sciences, and pharmacy.
The research will be conducted in the theoretical biochemistry research group of Prof Leif A. Eriksson. Focus is on modeling protein-protein and ligand-protein interactions of relevance in cancer research and development of novel pharmaceuticals. The main systems to be studied are related to the UPRosome involving multiprotein complexes of mainly IRE1, RtcB, ABL and/or PTP1B, as well as different apoptotic systems with focus on the Death Inducing Signaling Complex (DISC). The research is conducted using advanced docking techniques, screening, molecular and metadynamics simulations and development of machine learning models.
Research involving modeling of protein complexes, virtual screening and development of inhibitors capable of disrupting said complexes, molecular dynamics and metadynamics simulations, and development of machine learning models for the above systems. Supervision of project students and visiting PhD students. Administration of databases and usage of supercomputer resources (software updates, test of new software and methodology, assistance for other users in the group).
In order to be eligible to apply, a Swedish PhD degree, or equivalent foreign degree, I required. The degree must be within the areas physical chemistry, computational chemistry, biochemical modeling, or similar relevant area. The applicant must have documented experience of modeling of protein complexes, advanced simulation methodology and screening of databases, and be well accustomed to supercomputing environments. Experience in research at postdoctoral level is a merit, as is past supervision of students and knowledge about the systems to be investigated.
The employment is fixed term during 18 months at the Department of Chemistry and Molecular Biology
For further information regarding the position
Prof Leif Eriksson: email@example.com; +46 31 7869117
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How to apply
In order to apply for a position at the University of Gothenburg, you have to register an account in our online recruitment system. It is the responsibility of the applicant to ensure that the application is complete in accordance with the instructions in the job advertisement, and that it is submitted before the deadline. The selection of candidates is made on the basis of the qualifications registered in the application. The application must include CV, publications lsit, application letter including name of two references. Apply 2021-05-16
Closing date: 2021-05-16
The University of Gothenburg promotes equal opportunities, equality and diversity.
Salary is determined on an individual basis.
Applications will be destroyed or returned (upon request) two years after the decision of employment has become final. Applications from the employed and from those who appeal the decision will not be returned.
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